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April 2010


 



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Meet a Nobel Prize Scientist April 22 in Hartford
CURE Speaks Against 'Gifts' Bill
Health Network Plans Fortify Bioscience Sector
Arbor Fuel Presents at CURE/Yale BioHaven
CURE/Yale BioHaven Presents CardioPhotonics & Advanced Orthopedic Technologies
Connecticut Stem Cell Research Roundup
CURE Member News Digest

CURE/Yale BioHaven Presents CardioPhotonics & Advanced Orthopedic Technologies
 

    Continuing the 2009-2010 CURE/Yale BioHaven Entrepreneurship seminar series were presentations January 28 by Advanced Orthopedic Technologies and CardioPhotonics.

Introduced by Jon Soderstom of the Yale Office of Cooperative Research, the speakers were Thomas Wood, who is founding CEO of both companies; John Reach, M.Sc., M.D., who is an assistant professor at Yale University School of Medicine, for Advanced Orhtopedic Technologies; and Kirk Shelley, M.D., Ph.D., who is Professor of Anesthesiology at Yale University, for CardioPhotonics.

Advanced Orthopedic Technologies

Every year, millions of cartilage defects in the knee, ankle, and other joints are not treated or are treated sub-optimally because no method currently exists that can provide true hyaline cartilage and also address the variations in size, shape and topography of individual joints. 

Dr. John Reach of Yale envisioned a better system that would preserve the mobility and vitality of millions of orthopedic patients.

The company's product is a novel, proprietary clinical “solution” that provides the opportunity to successfully treat defects and improve the lives of patients suffering from joint disabilities.


The company's business plan is based upon addressing the significant underserved clinical need for hyaline cartilage for use in joint repair. This underserved need for hyaline cartilage is well established and results in the inability to adequately treat patients with focal osteochondral defects or osteoarthritis.

The company's technology has the potential to address markets totaling more than $1 billion. Potential markets include focal osetochondral defects and osteoarthriris.

In April 2009, Elm Street Ventures invested $250,000 as part of a $500,000 commitment to the company.

CardioPhotonics

Invented by Dr. Kirk Shelley and and Dr. David Silverman of Yale, the company's technology provides real-time, non-invasive blood volume monitoring with readings that are accurate from the first signal and sensitive to less than a unit of blood, thus providing clinicians with actionable data, including immediate fluid responsiveness feedback.

The company's goal is to develop an integrated set of products that are effective across all major causes of fluid volume change, in both hospital and non-hospital settings.

The company has developed a working prototype for mechanically ventilated patients that is being used regularly as part of a Yale clinical investigation. The results to date are consistent with expectations. Studies and development are ongoing for spontaneous breathing patients. The data to date is encouraging.

The company's technology has the potential to address markets totaling $2 billion. Potential markets include hospital surgery, ICU/CCU, renal dialysis, and cardiac units; emergency room and trauma transport applications; and military and geriatric markets.

Presented by CURE and the Yale Office of Cooperative Research, the BioHaven Series thanks its lead sponsors, Wiggin and Dana and PricewaterhouseCoopers. The series is also sponsored by Elm Street Ventures, with additional support from the Yale Entrepreneurial Institute and the Yale Biotechnology & Pharmaceutical Society.

 
 
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