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Thursday, January 28, 2010 Advanced Orthopedic Technologies Presentations followed by networking, refreshments & wine bar Advanced Orthopedic Technologies is a seed-stage company dedicated to treating cartilage defects in virtually any joint in the body. CardioPhotonics is a seed-stage company dedicated to identifying and developing noninvasive technologies to detect and understand changes in an individual’s fluid volume, facilitating clinical decisions and improving outcomes. Advanced Orthopedic Technologies Every year, millions of cartilage defects in the knee, ankle, and other joints are not treated or are treated sub-optimally because no method currently exists that can provide true hyaline cartilage and also address the variations in size, shape and topography of individual joints. Dr. John Reach of Yale envisioned a better system that would preserve the mobility and vitality of millions of orthopedic patients. The company's product is a novel, proprietary clinical “solution” that provides the opportunity to successfully treat defects and improve the lives of patients suffering from joint disabilities.The company's business plan is based upon addressing the significant underserved clinical need for hyaline cartilage for use in joint repair. This underserved need for hyaline cartilage is well established and results in the inability to adequately treat patients with focal osteochondral defects or osteoarthritis. The company's technology has the potential to address markets totaling more than $1 billion. Potential markets include focal osetochondral defects and osteoarthriris. In April 2009, Elm Street Ventures invested $250,000 as part of a $500,000 commitment to the company. CardioPhotonics Invented by Dr. Kirk Shelley and and Dr. David Silverman of Yale, the company's technology provides real-time, non-invasive blood volume monitoring with readings that are accurate from the first signal and sensitive to less than a unit of blood, thus providing clinicians with actionable data, including immediate fluid responsiveness feedback. The company's goal is to develop an integrated set of products that are effective across all major causes of fluid volume change, in both hospital and non-hospital settings. The company has developed a working prototype for mechanically ventilated patients that is being used regularly as part of a Yale clinical investigation. The results to date are consistent with expectations. Studies and development are ongoing for spontaneous breathing patients. The data to date is encouraging.The company's technology has the potential to address markets totaling $2 billion. Potential markets include hospital surgery, ICU/CCU, renal dialysis, and cardiac units; emergency room and trauma transport applications; and military and geriatric markets. The BioHaven Entrepreneurship Series features presentations designed to showcase regionally developed life science technologies that have progressed along the path to commercialization. Speakers at the BioHaven events represent both the scientific and business side of the enterprises. The programs focus on key success factors of each company, scientific or technological advantage, business model, and lessons learned in starting and developing the business. The series also provides social networking opportunities for scientists, researchers, and businessmen. For a calendar of all the 2009-10 BioHaven events, click here. Speakers
Thursday, January 28, 2010 Location Directions & Parking: RSVP Lead sponsors: Wiggin and Dana and PricewaterhouseCoopers.
Presented by CURE and the Yale Office of Cooperative Research.
Additional support from the Yale Entrepreneurial Institute and the Yale Biotechnology & Pharmaceutical Society.
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Quick Cut & Paste for Your
Calendar CURE/Yale BioHaven presents Advanced Orthopedic Technologies & CardioPhotonics 300 Cedar Street, New Haven Thurs Jan 28 2010 4:00 pm
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