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UConn researchers have generated 10 new stem cell lines from the cells of patients with a genetic disorder called Angelman syndrome, that enable them to watch how the disorder unfolds in petri dishes. It is hoped that the study of these cell lines will provide clues into the root causes of Angelman syndrome by revealing what goes right or wrong as the cells develop. This information could then be utilized in searching for and developing new therapies for treating the disorder. "We are generating individualized stem cells to create in vitro models of human disease," says Marc Lalande, director of UConn’s Stem Cell Institute. more